CAN DEPRESSION TREATMENT NOT WORK BECAUSE OF OBSTRUCTIVE SLEEP APNEA? - creativejournal @ ウィキ

Scientists have conducted a new study, which concluded that when a person is depressed or has suicidal thoughts and treatment for depression does not seem to work, they should check for obstructive sleep apnea.

Moreover, they agree that inquiries can be performed even though people do not appear to match the normal description of obstructive sleep apnea, which involves overweight men who snore and suffer from drowsiness during the day.

"No one is talking about evaluating obstructive sleep apnea as a potential cause of resistance to treatment for depression, which occurs in about 50% of cases of major depressive disorder," says W. Vaughn McCall, lead author of the study.

The researchers found this disease clinically relevant in 14% of the 125 patients diagnosed with major depressive disorder, insomnia, and suicidal thoughts.

McCall even claims that the existing evidence is sufficient to introduce obstructive sleep apnea testing into the standard procedure for managing resistance to depression treatment.

Most people diagnosed with apnea have higher rates of depression compared to other segments of the population. However, when things are reversed, specialists no longer have so much information.

The initial intention of the scientists was to find out if treating insomnia can reduce suicidal thoughts. Patients diagnosed with obstructive sleep apnea have been excluded because sleeping pills tend to relax the muscles, and in the case of apnea, the neck muscles are already too relaxed, which is a problem. People with morbid obesity were also excluded.

Of the 125 enrolled people tested through a sleep study, either in the center or at home, 17 were diagnosed with obstructive sleep apnea. However, neither daytime sleepiness nor insomnia accurately predicted the severity of apnea identified in the 17 patients, who were not obese, and six were women.

Treating apnea can improve the symptoms of depression

It is recognized that undetected medical or psychiatric conditions may cause resistance to treatment for depression. However, obstructive sleep apnea was not on this long list, including endocrine disorders such as hypothyroidism and other problems such as coronary heart disease and cancer.

Patients with obstructive sleep apnea often also have depressive symptoms. Also, patients with apnea do not respond well to antidepressants.

45% of the 125 participants were resistant to depression, and four of the 17 diagnosed with apnea had serious problems. Also, most participants with apnea were elderly, with the risk increasing as people get older.

Ten years earlier, McCall noticed that 8.2 percent of people with mild apnea had been studied in 73 patients with stress and insomnia, albeit with a low incidence of sleep apnea. Following a review by other specialists, 14% of 703 people with depression still had apnea. This is the first research in which suicidal behavior was indeed a consideration.

When people lose their last hope that they will sleep well, they have a high risk of suicide.

Obstructive sleep apnea appears to induce excess resting periods throughout the day, but insomnia patients have been enrolled in this experiment, and most of the individuals identified with insomnia are not prone to apnea. Depression aversion can also be a side-effect of drugs commonly used for other medical problems, including lupus and rheumatoid arthritis.

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