PC-PLC specific inhibitor is D609.
Look up PC-PLC in Pubmed
1.This reagent is used with 100 microM
in this paper.
D609 inhibits the proliferation of neural progenitor cells.
2.This paper is interesting!
This paper shows with PC-PLC antibody that PC-PLC activity is there on the outer leaflet of plasma membrane!
They use 50 μg/mL D609 for 24 hour, leading to downregulation of PC-PLC activity.
Inhibition of phosphatidylcholine-specific phospholipase C downregulates HER2 overexpression on plasma membrane of breast cancer cells.
最終更新:2010年07月02日 19:59