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meta-metabolome


2010


Metagenomics and Ecosystems Biology: Conceptual Frameworks, Tools and Methods

... in such environments. Analyses of the meta-metabolome Metabolomics is the study of all the naturally occurring small molecules, called metabolites, in biological samples such as cells, biofluids, and tissues. These small molecules ...

Signatures of Arithmetic Simplicity in Metabolic Network

WJ Riehl, PL Krapivsky, S Redner, D Segrè - 2010 - ncbi.nlm.nih.gov
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848538/
... some fundamental aspects of the architecture of metabolism may be visible only at the ecosystem-level, namely by collectively analyzing the metabolic network obtained as the union of the metabolic maps of known individual species (sometimes called the “meta-metabolome”). ...

Beyond Metagenomics: Integration of Complementary Approaches for the Study of Microbial Communities

Page 26. 2 Beyond Metagenomics: Integration of Complementary Approaches for the Study of Microbial Communities Andrés Cubillos-Ruiz, Howard Junca, Sandra Baena, Ivonne Venegas and María Mercedes Zambrano Abstract ...


2008


Host-bacterial coevolution and the search for new drug targets

J Zaneveld, PJ Turnbaugh, C Lozupone, RE … - Current opinion in …, 2008 - Elsevier
http://linkinghub.elsevier.com/retrieve/pii/S1367593108000082
... of our human biology thus requires the understanding of our microbial communities and the genes that they harbor ('our' microbiome) (Figure 1). The notion that we have a 'meta-genome' composed of microbial and human components, and a 'meta-metabolome' that reflects ...


2007


The human microbiome project

PJ Turnbaugh, RE Ley, M Hamady, CM Fraser-Liggett, … - Nature, 2007 - nature.com
http://www.nature.com/nature/journal/v449/n7164/full/nature06244.html
... comparative genomics to an integrated 'systems metagenomics' approach that accounts for microbial community structure (the microbiota), gene content (the microbiome), gene expression (the 'meta-transcriptome' and 'meta-proteome') and metabolism (the 'meta-metabolome'). ...

Human Metabolome Database: completing the 'human parts list'

DS Wishart - Pharmacogenomics, 2007 - Future Medicine
http://www.futuremedicine.com/doi/abs/10.2217/14622416.8.7.683?journalCode=pgs
... is of considerable interest to nutritional chemists. In an effort to capture this 'meta' metabolome, or nutrient metabolome, a separate database called FooDB is being developed [101]. Built using the same technology and annotated ...


2006


The effect of oxygen on biochemical networks and the evolution of complex life

J Raymond, D Segre - Science, 2006 - scienceonline.org
... is a collection of data from across known genomes, these metabol- ic networks correspond not to the reactions tenable within any one organism but to the meta- bolic potential of the collective (and currently characterized) biosphere that can be thought of as a meta-metabolome. ...

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最終更新:2010年06月02日 21:49