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Metabolic pathway analysis: basic concepts and scientific applications in the post-genomic erapsu.edu [PDF]
This article reviews the relatively short history of metabolic pathway analysis. Computer-aided algorithms for the synthesis of metabolic pathways are discussed. Important algebraic concepts used in pathway analysis, such as null space and convex cone, are explained. It is ...
Metabolic pathway analysisS Schuster - Information and Simulation Systems for the Analysis of … - Citeseer
18 Metabolic pathway analysis Stefan Schuster Max Delbruck Centre for Molecular Medicine D-13092 Berlin-Buch, Germany
Metabolic network analysis, alternatively called pathway analysis, has manifold applications in functional genomics, metabolic engineering and ...
Two approaches for metabolic pathway analysis?
Metabolic pathway analysis is becoming increasingly important for assessing inherent network properties in (reconstructed) biochemical reaction networks. Of the two most promising concepts for pathway analysis, one relies on elementary flux modes and the other on extreme ...
Theory for the systemic definition of metabolic pathways and their use in interpreting metabolic function from a pathway-oriented perspective
... 4193–4198. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (78). 25. CH SCHILLING, S. SCHUSTER, BO PALSSON and R. HEINRICH, Metabolic pathway analysis: basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. ...
A multiple alignment algorithm for metabolic pathway analysis using enzyme hierarchy
In many of the chemical reactions in living cells, enzymes act as catalysts in the conversion of certain compounds (substrates) into other compounds (products). Comparative analyses of the metabolic pathways formed by such reactions give important information on their ...
Metabolic pathway analysis of a recombinant yeast for rational strain development
Abstract: Elementary mode analysis has been used to study a metabolic pathway model of a recombinant Saccharomyces cerevisiae system that was genetically engineered to produce the bacterial storage compound poly-b-hydroxybutyrate (PHB). The model includes bio- ...
Metabolic pathway analysis web service (Pathway Hunter Tool at CUBIC)
Motivation: Pathway Hunter Tool (PHT), is a fast, robust and user-friendly tool to analyse the shortest paths in metabolic pathways. The user can perform shortest path analysis for one or more organisms or can build virtual organisms (networks) using enzymes. Using PHT, the ...
Combined use of proteomic analysis and enzyme activity assays for metabolic pathway analysis of glycerol fermentation by Klebsiella pneumoniae
Abstract: The fed-batch fermentation of glycerol to 1,3- propanediol by Klebsiella pneumoniae displayed an un- usual dynamic behavior that can be clearly divided into four distinct phases according to cell growth and CO2 evolution rate. Metabolism changed significantly during ...
Combinatorial complexity of pathway analysis in metabolic networks
Key words: combinatorial complexity in metabolic networks, elementary flux modes, metabolic pathway analysis, structural network analysis Summary Elementary flux mode analysis is a promising approach for a pathway ...
Comparison of network-based pathway analysis methods
... Recent network-based metabolic pathway analysis has focused on two approaches, those of elementary modes [4] and extreme pathways [5]. Both of these methods use convex analysis [6], a branch of mathematics that enables the analysis of inequalities and systems of linear ...
最終更新：2010年09月28日 21:31
