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Genome-scale reconstruction of the metabolic network in Staphylococcus aureus N 315: an initial draft to the two-dimensional annotation
... J Biol Chem 2004, 279:39532-39540. PubMed Abstract | Publisher Full Text OpenURL. Papp B, Pal C, Hurst LD:
Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast. Nature 2004, 429:661-664. ...
Adaptive evolution of bacterial metabolic networks by horizontal gene transfer
... were present. Gene families with more than one member in E. coli K-12 were excluded from the analysis. Metabolic network analysis. We examined the reconstructed metabolic network (iJR904 GSM/GPR) of E. coli K-12. We ...
Network analysis of metabolic enzyme evolution in Escherichia coli
... representation of metabolic pathways where the substrates and products are the vertices and the enzymes catalyzing the reactions are the edges (Figure 1). The type of network representation used in our study has been used before for metabolic network analysis where it has ...
Metabolic network analysis on Phaffia rhodozyma yeast using 13C-labeled glucose and gas chromatography-mass spectrometry
Amino acid labeling patterns, as determined by GC–MS, were in accordance with a metabolic network consisting of the Embden–Meyerhof–Parnas pathway, the pentose phosphate pathway, and the TCA cycle. Glucose was mainly consumed along the pentose ...
Metabolic network analysis integrated with transcript verification for sequenced genomes
Present availability of genome sequences for diverse microorganisms brings opportunities for metabolic engineering through systems-level characterization of these organisms' metabolic networks 1 . Such efforts require both functional and structural annotation of metabolic ...
High-throughput metabolic flux analysis based on gas chromatography-mass spectrometry derived 13C constraints
Influence of metabolic network structure and function on enzyme evolution
... Cold Spring Harbor Press, NY; 1982. OpenURL. Papp B, Pal C, Hurst LD Metabolic network analysis of the causes and evolution of the enzyme dispensability in yeast. Nature 2004,429:661-664. PubMed Abstract | Publisher Full Text OpenURL. ...
Metabolomics-and proteomics-assisted genome annotation and analysis of the draft metabolic network of Chlamydomonas reinhardtii
... Furthermore, the results will contribute to an improvement of metabolic databases. Presently, our methods are limited to one selected large-scale metabolic network analysis technique, the method of network expansion. Further ...
Metabolic network analysis during fed-batch cultivation of Corynebacterium glutamicum for pantothenic acid production: first quantitative data and analysis of by- …
A first generation genetically modified strain of Corynebacterium glutamicum has been assessed for its potential to synthesise and accumulate the vitamin pantothenic acid in the medium using fed-batch cultivation technology, with biomass concentration controlled by isoleucine ...
Metabolic modeling of microbial strains in silico
... labeling experiments. Adv. Biochem. Eng. Biotechnol. 54, pp. 109–154. Christensen, B. and Nielsen, J., Metabolic network analysis. A powerful tool in metabolic engineering. Adv. Biochem. Eng. Biotechnol. 66, pp. 209–231. The ...
最終更新:2010年09月28日 21:00