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Development of network-based pathway definitions: the need to analyze real metabolic networks
... A recent article [1] addresses the important issue of network-based metabolic pathway analysis. ... References 1 Klamt, S. and Stelling, J. (2003) Two approaches for metabolic pathway analysis? Trends Biotechnol. 21, 64–69 2 Karp, PD et al. ...
PathFinder: reconstruction and dynamic visualization of metabolic pathways
... database. Nucleic Acids Res., 26, 43–45. Tohsato,Y., Matsuda,H. and Hashimoto,A.(2000) A multiple align- ment algorithm for metabolic pathway analysis using enzyme hierarchy. Proceedings, ISMB 2000. pp. 376–383. Wackett ...
Toward metabolic phenomics: analysis of genomic data using flux balances
... This approach of metabolic pathway analysis accompanied with FBA techniques can allow one to assess the basic structural capabilities and fitness of an organism as a result of the pathways that are theoretically present within the cell. ...
Robustness Analysis of the Escherichiacoli Metabolic Network
Page 1. Robustness Analysis of the Escherichia coli Metabolic Network Jeremy S.Edwards† and Bernhard O. Palsson* Department of Bioengineering, University of California-San Diego, La Jolla, California 92093-0412 Genomic ...
FluxAnalyzer: exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps
... additionally reversibility and capacity restrictions for each reaction. Metabolic Pathway Analysis (MPA) searches for meaningful structural and functional units in metabolic networks. The two most promising, very similar ap- proaches ...
Integrating cybernetic modeling with pathway analysis provides a dynamic, systems-level description of metabolic control
... biochemical networks. Combining cybernetic control laws with concepts from metabolic pathway analysis has culminated in a sys- tematic strategy for constructing cybernetic models, which was previously lacking. The newly ...
Exploring the pathway structure of metabolism: decomposition into subnetworks and application to Mycoplasma pneumoniae
Page 1. BIOINFORMATICS Vol. 18 no. 2 2002 Pages 351–361 Exploring the pathway structure of metabolism: decomposition into subnetworks and application to Mycoplasma pneumoniae S. Schuster 1 , T. Pfeiffer 2 , F. Moldenhauer 1 , I. Koch 3 and T. Dandekar 4, 5 ...
The complete genome sequence of the gastric pathogen Helicobacter pylori
... Top of page Metabolism.
Metabolic pathway analysis of the H. pylori genome suggests the following features. H. pylori uses glucose as the only source of carbohydrate and the main source for substrate-level phosphorylation. ...
Deriving phylogenetic trees from the similarity analysis of metabolic pathways
Page 1. BIOINFORMATICS Vol. 19 Suppl. 1 2003, pages i138–i146 DOI:10.1093/bioinformatics/btg1018 Deriving phylogenetic trees from the similarity analysis of metabolic pathways Maureen Heymans and Ambuj K. Singh ∗ ...
Treatment of multifunctional enzymes in metabolic pathway analysis
In metabolic pathway analysis, it should be considered that many enzymes operate with low specificity (eg nucleoside diphosphokinase, uridine kinase, transketolase, aldolase), so that various substrates and products can be converted. Here, we analyze the effect of ...
最終更新:2010年09月28日 21:54