Metabolic network analysis 4 - Metal Meta-Metabolome Project

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Metabolic network analysis of Streptomyces tenebrarius, a Streptomyces species with an active Entner-Doudoroff pathway

nih.gov [HTML]I Borodina, C Scholler, A Eliasson, J … - Applied and …, 2005 - Am Soc Microbiol
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Streptomyces tenebrarius is an industrially important microorganism, producing an antibiotic complex that mainly consists of the aminoglycosides apramycin, tobramycin carbamate, and kanamycin B carbamate. When S. tenebrarius is used for industrial tobramycin ...

Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network

J Lee, H Yun, AM Feist, BØ Palsson, SY Lee - Applied microbiology and …, 2008 - Springer
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Page 1. GENOMICS AND PROTEOMICS Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network Joungmin Lee & Hongseok Yun & Adam M. Feist & Bernhard Ø. Palsson & Sang Yup Lee ...

Metabolic networks in motion: 13C-based flux analysis

nih.gov [HTML]U Sauer - Molecular systems biology, 2006 - nature.com
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... Curr Opin Biotechnol 16: 350–355 | Article | PubMed | ISI | ChemPort |; Borodina I, Schöller C, Eliasson A, Nielsen J (2005) Metabolic network analysis of Streptomyces tenebrarius, a Streptomyces species with an active Entner–Doudoroff pathway. ...

Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks

hindawi.com [PDF]O Fiehn - Comparative and Functional Genomics, 2001 - Wiley Online Library
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... Metabolomics. The obvious next step in metabolic network analysis is to try to determine metabolic snapshots in a broad and comprehensive way. ... 13 Christensen B, Nielsen J. Metabolic network analysis: a powerful tool in metabolic engineering. ...

A metabolic network analysis & NMR experiment design tool with user interface-driven model construction for depth-first search analysis

T Zhu, C Phalakornkule, S Ghosh, IE Grossmann, … - Metabolic …, 2003 - Elsevier
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A Windows program for metabolic engineering analysis and experimental design has been developed. A graphical user interface enables the pictorial, “on-screen” construction of a metabolic network. Once a model is composed, balance equations are automatically generated. ...

Genome-scale reconstruction and analysis of the Pseudomonas putida KT2440 metabolic network facilitates applications in biotechnology

plos.org [HTML]J Puchałka, MA Oberhardt, M Godinho, A Bielecka, … - PLoS Comput …, 2008 - dx.plos.org
PLoS Computational Biology is an open-access.
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Integrated analysis of regulatory and metabolic networks reveals novel regulatory mechanisms in Saccharomyces cerevisiae

cshlp.org [HTML]MJ Herrgård, BS Lee, V Portnoy, BØ … - Genome research, 2006 - genome.cshlp.org
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... biomass composition). The integration of the metabolic network analysis and the transcriptional regulatory network model described above is accomplished using the regulated flux balance analysis approach (Covert et al. 2001). In ...

Validation of a metabolic network for Saccharomyces cerevisiae using mixed substrate studies

ulaval.ca [PDF]PA Vanrolleghem, P de Jong-Gubbels, … - Biotechnology …, 1996 - interscience.wiley.com
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Page 1. ARTICLES Validation of a Metabolic Network for Saccharomyces cerevisiae Using Mixed Substrate Studies Peter A. Vanrolleghem,*,† Patricia de Jong-Gubbels,‡ Walter M. van Gulik,§ Jack T. Pronk,‡ Johannes P. van Dijken,‡ and Sef Heijnen† ...

Metabolic‐flux analysis of Saccharomyces cerevisiae CEN. PK113‐7D based on mass isotopomer measurements of 13C‐labeled primary metabolites

WA Winden, JC Dam, C Ras, RJ Kleijn, JL … - FEMS yeast …, 2005 - Wiley Online Library
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The efficiency of multi-target drugs: the network approach might help drug design

arxiv.org [PDF]P Csermely, V Agoston, S Pongor - Trends in pharmacological sciences, 2005 - Elsevier
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... 6111–6121. Full Text via CrossRef | View Record in Scopus | Cited By in Scopus (53). 8 B. Papp et al., Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast, Nature 429 (2004), pp. 661–664. Full Text via CrossRef | View Record in Scopus |.