Metabolic pathway/network analysis - Metal Meta-Metabolome Project

74. Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose

nih.gov [HTML]P Kiefer, E Heinzle, O Zelder, C … - Applied and …, 2004 - Am Soc Microbiol

... A comprehensive approach to 13 C tracer studies, labeling measurements by gas chromatography-mass spectrometry, metabolite balancing, and isotopomer modeling, was applied for comparative metabolic network analysis of lysine-producing Corynebacterium glutamicum ...

70. It is all about metabolic fluxes

nih.gov [HTML]J Nielsen - Journal of bacteriology, 2003 - Am Soc Microbiol
http://scholar.google.com/scholar?q=related:xAvLLrdbbNYJ:scholar.google.com/&hl=ja&as_sdt=2000

... I. Experimental observations. Biotechnol. Bioeng. 55:305-316.[CrossRef] 21; Thykaer, J., B. Christensen, and J. Nielsen. 2002. Metabolic network analysis of an adipoyl-7-ADCA producing strain of Penicillium chrysogenum: elucidation of adipate degradation.Metab. Eng. ...

47. In vivo analysis of intracellular amino acid labelings by GC/MS.

C Wittmann, M Hans, E Heinzle - Analytical biochemistry, 2002 - mendeley.com

... TBDMS derivatization of amino acids is especially useful in metabolic network analysis, because M-57 fragments containing the entire carbon skeleton of the analyte can be observed by GC/MS with high signal intensities 8. The potential of the method is exemplified for ...